The Treaty of the Holston was signed in 1791 by representatives of the United States and the Cherokee Nation. It ended the hostilities between the two nations, set boundaries, and allowed settlers to travel down the Tennessee River. In return for safe travel, the Cherokee nation received a one thousand dollar annuity and trade goods.
This monument by the point where First Creek empties into the Tennessee River is very close to the actual spot of the treaty signing. Here is the full view: